NEW STEP BY STEP MAP FOR CX-5461

Our results emphasize the potential of exploiting TOP1 inhibition to generally be coupled with CX-5461 being a non-genotoxic solution in targeting HR-proficient HGSC.CX-5461 also induces worldwide replication pressure connected to stalling and destabilization of replication forks by way of MRE11 action resulting in DNA damage, S-section and G2/M mo